Chinina solfato diidrato, Pharmpur®, Ph Eur, BP, USP

- Synonyms: Quinamm, Quine, Quinate, Quinsam
- (C20H24N2O2)2·H2SO4·2H2O
- M = 782,94 g/mol
- CAS [6119-70-6]
- EINECS-No.: 212-359-2
- Solub. in water: (20 ºC): ~ 1,2 g/l
- Melting point: 233 - 235 °C
- GHS-signal word: Warning
- GHS-H sentences: H302 - H312 - H332
- GHS-P sentences: P261 - P280 - P321 - P301+P312 - P304+P340 - P501a
- Tariff number: 2939 21 00 00
- Applications: in the pharmaceutics industry, bactericide, antiseptic, in food industry, in pharma industry.

SPECIFICATIONS
assay (titration with HClO4, on dried sample) : 99,0 - 101,0 %
Identification TLC: passes test
identification B (EP): passes test
Identification C (EP) / A (USP): passes test
Identification sulfates: passes test
Identification B (USP): passes test
appearance of solution: passes test
pH (1 %, H2O): 5,7 - 6,6
specific rotation ([a]25/D, c = 2, HCl 0,1 M): - 235 º - - 245 º:
specific rotation ([a]20/D, c = 2 , HCl 0,1 M, on dried sample): - 237 º - - 245 º
chloroform-alcohol-insoluble substances: max. 0,1 %
limit of dihydroquinine sulfate: max. 10,0 %

other cinchona alkaloids:
dihydroquinine: max. 10 %
any impurity eluted before quinine: max. 5 %
any other impurities: max. 2,5 %
residue on ignition: max. 0,1 %
loss on drying (105 ºC): 3,0 - 5,0