Scharlab has available the original ProntoSIL columns manufactured by BISCHOFF Chromatography, made from ultrapure spherical silica (99,999%). Strict factory controls. The system of zero dead volume for precolumns is recommended by the manufacturer. It consists of a holder for the direct connection of the cartridge precolumn to the column. This system ensures zero dead volume on connection. Also available is a universal precolumn system adaptable to all systems and any column. Refills cartridges are the same. The design of the housing is what changes in each system. Both systems can accommodate Bischoff cartridges, 10x4,0mm and 20x4,0mm.