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Tris-(hydroxymethyl)-aminomethane, Pharmpur®, Ph Eur, BP

- Synonyms: 2-Amino-2-(hydroxymethyl)-1,3-propanediol, Tromethamine, THAM, TRIS buffer
- C4H11NO3
- M = 121,14 g/mol
- CAS [77-86-1]
- EINECS-No.: 201-064-4
- Solub. in water: (20 ºC): 800 g/l
- Melting point: 172 - 173 ºC
- Boiling point: (13,3 hPa) 219 - 220 ºC
- LD 50 (oral, rat): 5900 mg/kg
- GHS-signal word: Warning
- GHS-H sentences: H315 - H319
- GHS-P sentences: P280 - P264 - P305+P351+P338 - P321 - P332+P313 - P337+P313
- Tariff number: 2922 19 00
- Applications: analytical chemistry, in buffer solutions, in biochemistry, laboratory reagent, in the pharmaceutics industry, emulsifier (cosmetics), for the synthesis of: tensoactives.

SPECIFICATIONS
assay (acidimetric, referred to dried sample): 99,0 - 100,5 %
Identification A (EP): passes test
Identification D (EP): passes test
Identification IR: passes test
melting point: 168 - 174 ºC
pH (5 %, H2O): 10,0 - 11,5
appearance of solution: clear and colourless
chlorides (Cl): max. 100 ppm:
iron (Fe): max. 10 ppm

residue on ignition: max. 0,1 %
loss on drying (105 ºC): max. 0,5 %