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L-Tryptophan, Pharmpur®, Ph Eur, BP, USP

- Synonyms: (S)-a-Amino-1H-indole-3-propanoic acid
- C11H12N2O2
- M = 204,23 g/mol
- CAS [73-22-3]
- EINECS-No.: 200-795-6
- Solub. in water: (20 ºC): 10 g/l
- Melting point: 290 ºC (decomposes)
- LD 50 (oral, rat): 16000 mg/kg
- Tariff number: 2933 99 80 90
- Applications: in biochemistry, for pharmaceutical use, for determination of proteins, in pharma industry.

SPECIFICATIONS

dried sample) : 98,5 - 101,0 %
Identification TLC: passes test
Identification D (EP): passes test
appearance of solution: passes test
pH (1 %, H2O): 5,5 - 7,0
chlorides (Cl): max. 200 ppm
sulfates (SO4): max. 300 ppm
ammonium (NH4): max. 0,02 %
specific rotation ([a]20°/D, c = 10, H2O):
referred to dried sample): -33,0 - -30,0

iron (Fe): max. 20 ppm

any ninhydrin-positive substances: max. 0,2 %
total impurities: max. 0,5 %
impurity A and related substances:
impurity A: max. 10 ppm
sum of the impurities with a retention time less than that of tryptophan: max. 100 ppm:
sum of the impurities with a retention time greater than that of tryptophan, up to 1.8 times the retention time of N-acetyltryptophan: : max. 300 ppm
sum of the impurities with a retention time greater than that of tryptophan: max. 300 ppm
residue on ignition: max. 0,1 %
loss on drying (105 ºC): max. 0,3 %